Contact
Spokesperson
Prof. Dr. Ralf Ficner 
Tel.: +49 (0)551-39-14071
Fax: +49 (0)551-39-14082
SFB860 Secretary
Kathrin Fricke
Linda Hsu
Tel.: +49 (0)551-39-10972
Fax: +49 (0)551-39-14082
SFB860
Georg-August-Universität Göttingen
Abtl. Molekulare Strukturbiologie
Justus-von-Liebig-Weg 11
37077 Göttingen
Publications
View publication in year: 2012 | 20112013
Structural determinants and mechanism of mammalian CRM1 allostery.
Dölker, N., Blanchet, C.E., Voß, B., Haselbach, D., Kappel , C., Monecke,T., Svergun, D.I., Stark, H., Ficner, R., Zachariae, U., Grubmüller, H.and Dickmanns, A. .
Structure, 21:1350-1360. 2013.
Dölker, N., Blanchet, C.E., Voß, B., Haselbach, D., Kappel , C., Monecke,T., Svergun, D.I., Stark, H., Ficner, R., Zachariae, U., Grubmüller, H.and Dickmanns, A. .
Structure, 21:1350-1360. 2013.
The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-κB.
Ahmed, Y.L., Gerke, J., Park, H.-S., Bayram, Ö., Neumann, P., Min Ni, M., Dickmanns, A., Kim, S.C. , Yu, J.-H., Braus, G.H. and Ficner, R. .
PlosBiol., 11(12): e1001750. 2013.
Ahmed, Y.L., Gerke, J., Park, H.-S., Bayram, Ö., Neumann, P., Min Ni, M., Dickmanns, A., Kim, S.C. , Yu, J.-H., Braus, G.H. and Ficner, R. .
PlosBiol., 11(12): e1001750. 2013.
Structural basis for cooperativity of CRM1 export complex formation.
Monecke T, Haselbach D, Voß B, Russek A, Neumann P, Thomson E, Hurt E, Zachariae U, Stark H, Grubmüller H, Dickmanns A, Ficner R.
Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):960-5. doi: 10.1073/pnas.1215214110.
Monecke T, Haselbach D, Voß B, Russek A, Neumann P, Thomson E, Hurt E, Zachariae U, Stark H, Grubmüller H, Dickmanns A, Ficner R.
Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):960-5. doi: 10.1073/pnas.1215214110.
Propranolol Restricts the Mobility of Single EGF-Receptors on the Cell Surface before Their Internalization.
Carolina Otero, Max Linke, Paula Sanchez, Alfonso González, Iwan A. T. Schaap
PLos One. 2013 8 (12):e83086
Carolina Otero, Max Linke, Paula Sanchez, Alfonso González, Iwan A. T. Schaap
PLos One. 2013 8 (12):e83086
Cutting Edge: Feed-Forward Activation of Phospholipase Cγ2 via C2 Domain-Mediated Binding to SLP65.
Engelke M, Oellerich T, Dittmann K, Hsiao HH, Urlaub H, Serve H, Griesinger C, Wienands J.
J Immunol. 2013 Dec 1;191(11):5354-8. doi: 10.4049/jimmunol.1301326.
Engelke M, Oellerich T, Dittmann K, Hsiao HH, Urlaub H, Serve H, Griesinger C, Wienands J.
J Immunol. 2013 Dec 1;191(11):5354-8. doi: 10.4049/jimmunol.1301326.
Monosome Formation during Translation Initiation Requires the Serine/Arginine-Rich Protein Npl3.
Baierlein C, Hackmann A, Gross T, Henker L, Hinz F, Krebber H.
Mol Cell Biol. 2013 Dec;33(24):4811-23. doi: 10.1128/MCB.00873-13.
Baierlein C, Hackmann A, Gross T, Henker L, Hinz F, Krebber H.
Mol Cell Biol. 2013 Dec;33(24):4811-23. doi: 10.1128/MCB.00873-13.
A high-speed vertical optical trap for the mechanical testing of living cells at piconewton forces .
Bodensiek K, Li W, Sánchez P, Nawaz S, Schaap IA.
Rev Sci Instrum. 2013 Nov;84(11):113707.
Bodensiek K, Li W, Sánchez P, Nawaz S, Schaap IA.
Rev Sci Instrum. 2013 Nov;84(11):113707.
Energy barriers and driving forces in tRNA translocation through the ribosome.
Bock LV, Blau C, Schröder GF, Davydov II, Fischer N, Stark H, Rodnina MV, Vaiana AC, Grubmüller H.
Nat Struct Mol Biol. 2013 Nov 3. doi: 10.1038/nsmb.2690.
Bock LV, Blau C, Schröder GF, Davydov II, Fischer N, Stark H, Rodnina MV, Vaiana AC, Grubmüller H.
Nat Struct Mol Biol. 2013 Nov 3. doi: 10.1038/nsmb.2690.
Phosphorylation Drives a Dynamic Switch in Serine/Arginine-Rich Proteins.
Xiang S, Gapsys V, Kim HY, Bessonov S, Hsiao HH, Möhlmann S, Klaukien V, Ficner R, Becker S, Urlaub H, Lührmann R, de Groot B, Zweckstetter M.
Structure. 2013 Oct 30. pii: S0969-2126(13)00365-1. doi: 10.1016/j.str.2013.09.014. [Epub ahead of print]
Xiang S, Gapsys V, Kim HY, Bessonov S, Hsiao HH, Möhlmann S, Klaukien V, Ficner R, Becker S, Urlaub H, Lührmann R, de Groot B, Zweckstetter M.
Structure. 2013 Oct 30. pii: S0969-2126(13)00365-1. doi: 10.1016/j.str.2013.09.014. [Epub ahead of print]
RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.
Anokhina M, Bessonov S, Miao Z, Westhof E, Hartmuth K, Lührmann R.
EMBO J. 2013 Oct 30;32(21):2804-18. doi: 10.1038/emboj.2013.198.
Anokhina M, Bessonov S, Miao Z, Westhof E, Hartmuth K, Lührmann R.
EMBO J. 2013 Oct 30;32(21):2804-18. doi: 10.1038/emboj.2013.198.
Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry.
Christian H, Hofele RV, Urlaub H, Ficner R.
Nucleic Acids Res. 2013 Oct 27. [Epub ahead of print]
Christian H, Hofele RV, Urlaub H, Ficner R.
Nucleic Acids Res. 2013 Oct 27. [Epub ahead of print]
The YmdB phosphodiesterase is a global regulator of late adaptive responses in Bacillus subtilis.
Diethmaier C, Newman JA, Kovács AT, Kaever V, Herzberg C, Rodrigues C, Boonstra M, Kuipers OP, Lewis RJ, Stülke J.
J Bacteriol. 2013 Oct 25. [Epub ahead of print]
Diethmaier C, Newman JA, Kovács AT, Kaever V, Herzberg C, Rodrigues C, Boonstra M, Kuipers OP, Lewis RJ, Stülke J.
J Bacteriol. 2013 Oct 25. [Epub ahead of print]
Predicting the rotational tumbling of dynamic multidomain proteins and supramolecular complexes.
Rezaei-Ghaleh N, Klama F, Munari F, Zweckstetter M.
Angew Chem Int Ed Engl. 2013 Oct 18;52(43):11410-4. doi: 10.1002/anie.201305094.
Rezaei-Ghaleh N, Klama F, Munari F, Zweckstetter M.
Angew Chem Int Ed Engl. 2013 Oct 18;52(43):11410-4. doi: 10.1002/anie.201305094.
Sub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Lüdtke S, Neumann P, Erixon KM, Leeper F, Kluger R, Ficner R, Tittmann K.
Nat Chem. 2013 Sep;5(9):762-7. doi: 10.1038/nchem.1728.
Lüdtke S, Neumann P, Erixon KM, Leeper F, Kluger R, Ficner R, Tittmann K.
Nat Chem. 2013 Sep;5(9):762-7. doi: 10.1038/nchem.1728.
Observation of a stable carbene at the active site of a thiamin enzyme.
Meyer D, Neumann P, Ficner R, Tittmann K
Nat Chem Biol. 2013 Aug;9(8):488-90. doi: 10.1038/nchembio.1275.
Meyer D, Neumann P, Ficner R, Tittmann K
Nat Chem Biol. 2013 Aug;9(8):488-90. doi: 10.1038/nchembio.1275.
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.
Mozaffari-Jovin S, Wandersleben T, Santos KF, Will CL, Lührmann R, Wahl MC.
Science. 2013 Jul 5;341(6141):80-4. doi: 10.1126/science.1237515.
Mozaffari-Jovin S, Wandersleben T, Santos KF, Will CL, Lührmann R, Wahl MC.
Science. 2013 Jul 5;341(6141):80-4. doi: 10.1126/science.1237515.
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system.
Ohrt T, Odenwälder P, Dannenberg J, Prior M, Warkocki Z, Schmitzová J, Karaduman R, Gregor I, Enderlein J, Fabrizio P, Lührmann R.
RNA. 2013 Jul;19(7):902-15. doi: 10.1261/rna.039024.113.
Ohrt T, Odenwälder P, Dannenberg J, Prior M, Warkocki Z, Schmitzová J, Karaduman R, Gregor I, Enderlein J, Fabrizio P, Lührmann R.
RNA. 2013 Jul;19(7):902-15. doi: 10.1261/rna.039024.113.
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
Commichau FM, Pietack N, Stülke J.
Mol Biosyst. 2013 Jun 7;9(6):1068-75. doi: 10.1039/c3mb25595f.
Commichau FM, Pietack N, Stülke J.
Mol Biosyst. 2013 Jun 7;9(6):1068-75. doi: 10.1039/c3mb25595f.
Qualitative and quantitative characterization of protein-phosphoinositide interactions with liposome-based methods.
Busse RA, Scacioc A, Hernandez JM, Krick R, Stephan M, Janshoff A, Thumm M, Kühnel K.
Autophagy. 2013 May 1;9(5):770-7. doi: 10.4161/auto.23978.
Busse RA, Scacioc A, Hernandez JM, Krick R, Stephan M, Janshoff A, Thumm M, Kühnel K.
Autophagy. 2013 May 1;9(5):770-7. doi: 10.4161/auto.23978.
conF and conJ contribute to conidia germination and stress response in the filamentous fungus Aspergillus nidulans.
Suzuki S, Sarikaya Bayram O, Bayram O, Braus GH.
Fungal Genet Biol. 2013 May 1. pii: S1087-1845(13)00078-9. doi: 10.1016/j.fgb.2013.04.008.
Suzuki S, Sarikaya Bayram O, Bayram O, Braus GH.
Fungal Genet Biol. 2013 May 1. pii: S1087-1845(13)00078-9. doi: 10.1016/j.fgb.2013.04.008.
Dynamic localization of a transcription factor in Bacillus subtilis: The LicT antiterminator relocalizes in response to inducer availability.
Rothe FM, Wrede C, Lehnik-Habrink M, Görke B, Stülke J.
J Bacteriol. 2013 May;195(10):2146-54. doi: 10.1128/JB.00117-13.
Rothe FM, Wrede C, Lehnik-Habrink M, Görke B, Stülke J.
J Bacteriol. 2013 May;195(10):2146-54. doi: 10.1128/JB.00117-13.
Alternating sites reactivity is a common feature of thiamin diphosphate-dependent enzymes as evidenced by isothermal titration calorimetry studies of substrate binding.
Schröder-Tittmann K, Meyer D, Arens J, Wechsler C, Tietzel M, Golbik R, Tittmann k.
Biochemistry. 2013 Apr 16;52(15):2505-7. doi: 10.1021/bi301591e.
Schröder-Tittmann K, Meyer D, Arens J, Wechsler C, Tietzel M, Golbik R, Tittmann k.
Biochemistry. 2013 Apr 16;52(15):2505-7. doi: 10.1021/bi301591e.
Structural plasticity in human heterochromatin protein 1β.
Munari F, Rezaei-Ghaleh N, Xiang S, Fischle W, Zweckstetter M.
PLoS One. 2013 Apr 9;8(4):e60887. doi: 10.1371/journal.pone.0060887.
Munari F, Rezaei-Ghaleh N, Xiang S, Fischle W, Zweckstetter M.
PLoS One. 2013 Apr 9;8(4):e60887. doi: 10.1371/journal.pone.0060887.
Dual use of GTP hydrolysis by elongation factor G on the ribosome.
Carlos E. Cunha, Riccardo Belardinelli, Frank Peske, Wolf Holtkamp, Wolfgang Wintermeyer, Marina V. Rodnina
Translation 2013; 1:e24315; http://dx.doi.org/10.4161/trla.24315
Carlos E. Cunha, Riccardo Belardinelli, Frank Peske, Wolf Holtkamp, Wolfgang Wintermeyer, Marina V. Rodnina
Translation 2013; 1:e24315; http://dx.doi.org/10.4161/trla.24315
Signal recognition initiates reorganization of the presequence translocase during protein import.
Lytovchenko O, Melin J, Schulz C, Kilisch M, Hutu DP, Rehling P.
EMBO J. 2013 Mar 20;32(6):886-98. doi: 10.1038/emboj.2013.23.
Lytovchenko O, Melin J, Schulz C, Kilisch M, Hutu DP, Rehling P.
EMBO J. 2013 Mar 20;32(6):886-98. doi: 10.1038/emboj.2013.23.
Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome.
Christmann M, Schmaler T, Gordon C, Huang X, Bayram O, Schinke J, Stumpf S, Dubiel W, Braus GH.
PLoS Genet. 2013 Feb;9(2):e1003275. doi: 10.1371/journal.pgen.1003275.
Christmann M, Schmaler T, Gordon C, Huang X, Bayram O, Schinke J, Stumpf S, Dubiel W, Braus GH.
PLoS Genet. 2013 Feb;9(2):e1003275. doi: 10.1371/journal.pgen.1003275.
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system.
Fourmann JB, Schmitzová J, Christian H, Urlaub H, Ficner R, Boon KL, Fabrizio P, Lührmann R.
Genes Dev. 2013 Feb 15;27(4):413-28. doi: 10.1101/gad.207779.112.
Fourmann JB, Schmitzová J, Christian H, Urlaub H, Ficner R, Boon KL, Fabrizio P, Lührmann R.
Genes Dev. 2013 Feb 15;27(4):413-28. doi: 10.1101/gad.207779.112.
Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants.
Skora L, Fonseca-Ornelas L, Hofele RV, Riedel D, Giller K, Watzlawik J, Schulz-Schaeffer WJ, Urlaub H, Becker S, Zweckstetter M.
J Biol Chem. 2013 Feb 1;288(5):2994-3002. doi: 10.1074/jbc.M112.423715
Skora L, Fonseca-Ornelas L, Hofele RV, Riedel D, Giller K, Watzlawik J, Schulz-Schaeffer WJ, Urlaub H, Becker S, Zweckstetter M.
J Biol Chem. 2013 Feb 1;288(5):2994-3002. doi: 10.1074/jbc.M112.423715
2012
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA.
Mozaffari-Jovin S, Santos KF, Hsiao HH, Will CL, Urlaub H, Wahl MC, Lührmann R.
Genes Dev. 2012 Nov 1;26(21):2422-34. doi: 10.1101/gad.200949.112.
Mozaffari-Jovin S, Santos KF, Hsiao HH, Will CL, Urlaub H, Wahl MC, Lührmann R.
Genes Dev. 2012 Nov 1;26(21):2422-34. doi: 10.1101/gad.200949.112.
DEAD-Box RNA helicases in Bacillus subtilis have multiple functions and act independently from each other.
Lehnik-Habrink M, Rempeters L, Kovács ÁT, Wrede C, Baierlein C, Krebber H, Kuipers OP, Stülke J.
J Bacteriol. 2013 Feb;195(3):534-44. doi: 10.1128/JB.01475-12.
Lehnik-Habrink M, Rempeters L, Kovács ÁT, Wrede C, Baierlein C, Krebber H, Kuipers OP, Stülke J.
J Bacteriol. 2013 Feb;195(3):534-44. doi: 10.1128/JB.01475-12.
Characterization of the velvet regulators in Aspergillus fumigatus.
Park HS, Bayram O, Braus GH, Kim SC, Yu JH.
Mol Microbiol. 2012 Nov;86(4):937-53. doi: 10.1111/mmi.12032.
Park HS, Bayram O, Braus GH, Kim SC, Yu JH.
Mol Microbiol. 2012 Nov;86(4):937-53. doi: 10.1111/mmi.12032.
Structural analysis of the C-terminal domain of the spliceosomal helicase Prp22.
Kudlinzki D, Schmitt A, Christian H, Ficner R.
Biol Chem. 2012 Sep 8;393(10):1131-40. doi: 10.1515/hsz-2012-0158.
Kudlinzki D, Schmitt A, Christian H, Ficner R.
Biol Chem. 2012 Sep 8;393(10):1131-40. doi: 10.1515/hsz-2012-0158.
Determinants of interaction specificity of the Bacillus subtilis GlcT antitermination protein: functionality and phosphorylation specificity depend on the arrangement of the regulatory domains.
Himmel S, Zschiedrich CP, Becker S, Hsiao HH, Wolff S, Diethmaier C, Urlaub H, Lee D, Griesinger C, Stülke J..
J Biol Chem. 2012 Aug 10;287(33):27731-42. doi: 10.1074/jbc.M112.388850.
Himmel S, Zschiedrich CP, Becker S, Hsiao HH, Wolff S, Diethmaier C, Urlaub H, Lee D, Griesinger C, Stülke J..
J Biol Chem. 2012 Aug 10;287(33):27731-42. doi: 10.1074/jbc.M112.388850.
MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation.
Mick DU, Dennerlein S, Wiese H, Reinhold R, Pacheu-Grau D, Lorenzi I, Sasarman F, Weraarpachai W, Shoubridge EA, Warscheid B, Rehling P.
Cell. 2012 Dec 21;151(7):1528-41. doi: 10.1016/j.cell.2012.11.053.
Mick DU, Dennerlein S, Wiese H, Reinhold R, Pacheu-Grau D, Lorenzi I, Sasarman F, Weraarpachai W, Shoubridge EA, Warscheid B, Rehling P.
Cell. 2012 Dec 21;151(7):1528-41. doi: 10.1016/j.cell.2012.11.053.
The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner.
Reinhold R, Krüger V, Meinecke M, Schulz C, Schmidt B, Grunau SD, Guiard B, Wiedemann N, van der Laan M, Wagner R, Rehling P, Dudek J.
Mol Cell Biol. 2012 Dec;32(24):5009-21. doi: 10.1128/MCB.00843-12
Reinhold R, Krüger V, Meinecke M, Schulz C, Schmidt B, Grunau SD, Guiard B, Wiedemann N, van der Laan M, Wagner R, Rehling P, Dudek J.
Mol Cell Biol. 2012 Dec;32(24):5009-21. doi: 10.1128/MCB.00843-12
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Santos KF, Jovin SM, Weber G, Pena V, Lührmann R, Wahl MC.
Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17418-23. doi: 10.1073/pnas.1208098109.
Santos KF, Jovin SM, Weber G, Pena V, Lührmann R, Wahl MC.
Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17418-23. doi: 10.1073/pnas.1208098109.
It takes two to tango: PROPPINs use two phosphoinositide-binding sites.
Thumm M, Busse RA, Scacioc A, Stephan M, Janshoff A, Kühnel K, Krick R.
Autophagy. 2012 Oct 15;9(1). doi: 10.1073/pnas.1205128109
Thumm M, Busse RA, Scacioc A, Stephan M, Janshoff A, Kühnel K, Krick R.
Autophagy. 2012 Oct 15;9(1). doi: 10.1073/pnas.1205128109
Methylation of lysine 9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome.
Munari F, Soeroes S, Zenn HM, Schomburg A, Kost N, Schröder S, Klingberg R, Rezaei-Ghaleh N, Stützer A, Gelato KA, Walla PJ, Becker S, Schwarzer D, Zimmermann B, Fischle W, Zweckstetter M.
J Biol Chem. 2012 Sep 28;287(40):33756-65.
Munari F, Soeroes S, Zenn HM, Schomburg A, Kost N, Schröder S, Klingberg R, Rezaei-Ghaleh N, Stützer A, Gelato KA, Walla PJ, Becker S, Schwarzer D, Zimmermann B, Fischle W, Zweckstetter M.
J Biol Chem. 2012 Sep 28;287(40):33756-65.
DExD/H-box RNA helicases in ribosome biogenesis.
Martin R, Straub AU, Doebele C, Bohnsack MT.
RNA Biol. 2013 Jan;10(1):4-18. doi: 10.4161/rna.21879
Martin R, Straub AU, Doebele C, Bohnsack MT.
RNA Biol. 2013 Jan;10(1):4-18. doi: 10.4161/rna.21879
The Aspergillus nidulans MAPK Module AnSte11-Ste50-Ste7-Fus3 Controls Development and Secondary Metabolism
Özgür Bayram, Özlem Sarikaya Bayram, Yasar Luqman Ahmed, Jun-ichi Maruyama, Oliver Valerius, Silvio O. Rizzoli, Ralf Ficner, Stefan Irniger, Gerhard H. Braus
PLoS Genet. 2012 Jul;8(7):e1002816., doi:10.1371/journal.pgen.1002816
Özgür Bayram, Özlem Sarikaya Bayram, Yasar Luqman Ahmed, Jun-ichi Maruyama, Oliver Valerius, Silvio O. Rizzoli, Ralf Ficner, Stefan Irniger, Gerhard H. Braus
PLoS Genet. 2012 Jul;8(7):e1002816., doi:10.1371/journal.pgen.1002816
Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family.
Roswitha Kricka, Ricarda A. Busseb, Andreea Scaciocb, Milena Stephanc, Andreas Janshoffc, Michael Thumm, Karin Kühnel
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):E2042-9. doi: 10.1073/pnas.1205128109
Roswitha Kricka, Ricarda A. Busseb, Andreea Scaciocb, Milena Stephanc, Andreas Janshoffc, Michael Thumm, Karin Kühnel
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):E2042-9. doi: 10.1073/pnas.1205128109
Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS.
Ohrt T, Prior M, Dannenberg J, Odenwälder P, Dybkov O, Rasche N, Schmitzová J, Gregor I, Fabrizio P, Enderlein J, Lührmann R.
RNA. 2012 Jun;18(6):1244-56. doi: 10.1261/rna.033316.112.
Ohrt T, Prior M, Dannenberg J, Odenwälder P, Dybkov O, Rasche N, Schmitzová J, Gregor I, Fabrizio P, Enderlein J, Lührmann R.
RNA. 2012 Jun;18(6):1244-56. doi: 10.1261/rna.033316.112.
RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases.
Martin Lehnik-Habrink, Richard J. Lewis, Ulrike Mäder and Jörg Stülke
Mol Microbiol. 2012 84(6), 1005–1017, doi:10.1111/j.1365-2958.2012.08072.x
Martin Lehnik-Habrink, Richard J. Lewis, Ulrike Mäder and Jörg Stülke
Mol Microbiol. 2012 84(6), 1005–1017, doi:10.1111/j.1365-2958.2012.08072.x
The COP9 signalosome counteracts the accumulation of cullin SCF ubiquitin E3 RING ligases during fungal development.
von Zeska Kress MR, Harting R, Bayram O, Christmann M, Irmer H, Valerius O, Schinke J, Goldman GH, Braus GH.
Mol Microbiol. 2012 Mar;83(6):1162-77. doi: 10.1111/j.1365-2958.2012.07999.x.
von Zeska Kress MR, Harting R, Bayram O, Christmann M, Irmer H, Valerius O, Schinke J, Goldman GH, Braus GH.
Mol Microbiol. 2012 Mar;83(6):1162-77. doi: 10.1111/j.1365-2958.2012.07999.x.
Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre.
Rasche N, Dybkov O, Schmitzová J, Akyildiz B, Fabrizio P, Lührmann R.
EMBO J. 2012 Mar 21;31(6):1591-604. doi: 10.1038/emboj.2011.502. Epub 2012 Jan 13.
Rasche N, Dybkov O, Schmitzová J, Akyildiz B, Fabrizio P, Lührmann R.
EMBO J. 2012 Mar 21;31(6):1591-604. doi: 10.1038/emboj.2011.502. Epub 2012 Jan 13.
2011
Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex.
Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P.
J Cell Biol. 2011 Nov 14;195(4):643-56. doi: 10.1083/jcb.201105098.
Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P.
J Cell Biol. 2011 Nov 14;195(4):643-56. doi: 10.1083/jcb.201105098.
A Novel Factor Controlling Bistability in Bacillus subtilis: The YmdB Protein Affects Flagellin Expression and Biofilm Formation.
Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J.
J Bacteriol. 2011 Nov;193(21):5997-6007. doi: 10.1128/JB.05360-11.
Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J.
J Bacteriol. 2011 Nov;193(21):5997-6007. doi: 10.1128/JB.05360-11.
The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.
Thomas Oellerich, Vanessa Bremes, Konstantin Neumann, Hanibal Bohnenberger, Kai Dittmann, He-Hsuan Hsiao, Michael Engelke, Tim Schnyder, Facundo Batista, Henning Urlaub and Jürgen Wienands
The EMBO Journal, 5 August 2011; doi:10.1038/emboj.2011.251
Thomas Oellerich, Vanessa Bremes, Konstantin Neumann, Hanibal Bohnenberger, Kai Dittmann, He-Hsuan Hsiao, Michael Engelke, Tim Schnyder, Facundo Batista, Henning Urlaub and Jürgen Wienands
The EMBO Journal, 5 August 2011; doi:10.1038/emboj.2011.251
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J.
Mol Microbiol., 4 Aug 2011; doi: 10.1111/j.1365-2958.2011.07777.
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J.
Mol Microbiol., 4 Aug 2011; doi: 10.1111/j.1365-2958.2011.07777.
RNase Y in Bacillus subtilis: a natively disordered protein that is the functional equivalent to RNase E from Escherichia coli.
Lehnik-Habrink M, Newman J, Rothe FM, Solovyova AS, Rodrigues C, Herzberg C, Commichau FM, Lewis RJ, Stülke J.
J Bacteriol, 2011 Oct;193(19):5431-41. doi: 10.1128/JB.05500-11.
Lehnik-Habrink M, Newman J, Rothe FM, Solovyova AS, Rodrigues C, Herzberg C, Commichau FM, Lewis RJ, Stülke J.
J Bacteriol, 2011 Oct;193(19):5431-41. doi: 10.1128/JB.05500-11.
Ran-dependent nuclear export mediators: a structural perspective.
Güttler T, Görlich D.
EMBO J. 2011 Aug 31;30(17):3457-74. doi: 10.1038/emboj.2011.287.
Güttler T, Görlich D.
EMBO J. 2011 Aug 31;30(17):3457-74. doi: 10.1038/emboj.2011.287.
The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits.
Hackmann A, Gross T, Baierlein C, Krebber H.
EMBO Rep. 2011 Sep 30;12(10):1024-31. doi: 10.1038/embor.2011.155.
Hackmann A, Gross T, Baierlein C, Krebber H.
EMBO Rep. 2011 Sep 30;12(10):1024-31. doi: 10.1038/embor.2011.155.
The signaling tool box for tyrosine-based costimulation of lymphocytes.
Engels N, Wienands J.
Curr Opin Immunol. 2011 Jun;23(3):324-9. doi: 10.1016/j.coi.2011.01.005.
Engels N, Wienands J.
Curr Opin Immunol. 2011 Jun;23(3):324-9. doi: 10.1016/j.coi.2011.01.005.
Spatiotemporal resolution of Ca2+ signaling events by real time imaging of single B cells.
Hanibal Bohnenberger, Thomas Oellerich, Michael Engelke, He-Hsuan Hsiao, Henning Urlaub, Jürgen Wienands
European journal of immunology, 25 May 2011; doi: 10.1002/eji.201041326
Hanibal Bohnenberger, Thomas Oellerich, Michael Engelke, He-Hsuan Hsiao, Henning Urlaub, Jürgen Wienands
European journal of immunology, 25 May 2011; doi: 10.1002/eji.201041326
Prevention of cross-talk in conserved regulatory systems: identification of specificity determinants in RNA-binding anti-termination proteins of the BglG family.
Hübner S, Declerck N, Diethmaier C, Le Coq D, Aymerich S, Stülke J.
Nucleic Acids Res, May 2011; 39(10):4360-72. doi: 10.1093/nar/gkr021
Hübner S, Declerck N, Diethmaier C, Le Coq D, Aymerich S, Stülke J.
Nucleic Acids Res, May 2011; 39(10):4360-72. doi: 10.1093/nar/gkr021