Symposium
Molecular machines in RNA processing,
translation and transport

Program (last update:12.02.2013) download pdf

Wednesday, Feb. 13

16:00 - 18:00     Registration
Session I (Chairperson: Ralf Ficner)
17:30 - 18:15     Tim Nilsen
Stable Translating Deadenylated mRNAs In Drosophila S2 Cells
18:15 - 18:35  Laurent Larivière
Structure of the Mediator head module
18:35 - 19:20 Karl-Peter Hopfner
Innate immune sensing of viral RNA by RIG-I like receptors
19:30 Dinner

 

Thursday, Feb. 14

08:30 - 11:00     Registration
Session II (Chairperson: Jörg Stülke)
09:00 - 09:45        Dagmar Klostermeier
Nucleic acid unwinding by SF2 helicase modules: A common theme and its variations
09:45 - 10:05    Debora Makino
The Crystal Structure of a Yeast 11-Subunit Exosome Complex Bound to RNA
10:05 - 10:50  Eckhard Jankowsky
How RNA helicase and poly(A) polymerase regulate each other in the TRAMP complex.
10:50 – 11:20 Coffee Break 
Session III (Chairperson: Jörg Enderlein)
11:20 - 12:05 David Lilley
k-turns in RNA : architecture and folding
12:05 - 12:50  Marat Yusupov
From crystallization of bacterial ribosome to structure determination of eukaryotic ribosome
13:15 – 14:15 Lunch
Session IV (Chairperson: Marina Rodnina)
14:30 - 14:50 Wolf Holtkamp
GTP hydrolysis by EF-G synchronizes tRNA translocation on small and large ribosomal subunits
14:50 - 15:10 Niels Fischer
Cryo-EM structure of the SelB-Sec-tRNASec- ribosome complex at 6 Å resolution
15:10 - 15:55  Charalampos Kalodimos
Structural basis for the progressive binding of nascent polypeptide chains by the trigger factor chaperone
16:00 – 16:30 Coffee Break
16:30 – 18:30   Poster Session
18:30 Dinner

Friday, Feb. 15

08:30 - 09:30     Registration
Session V (Chairperson: Markus Zweckstetter)
09:00 - 09:45        Frederic Allain
Splicing and translation regulation by small RNA binding protein
09:45 - 10:05    Thorsten Stafforst
Engineering Guide-RNA-Dependent Deaminases To Selectively Introduce Point Mutations Into mRNA
10:05 - 10:50  Utz Fischer
Structural insights into the assembly of RNA-protein complexes
10:50 – 11:20 Coffee Break 
Session VI (Chairperson: Henning Urlaub)
11:20 - 12:05  Jean Beggs
Cwc21p regulates intron branch site usage in splicing
12:05 - 12:25 Jean-Baptiste Fourmann
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system
12:25 - 13:10    Markus Wahl
Regulation of the Brr2 RNP remodeling enzyme during snRNP and spliceosome assembly
13:15 – 14:15 Lunch
Session VII (Chairperson: Reinhard Lührmann)
14:30 - 15:15 Douglas Black
Mechanisms of Splicing Regulation
15:15 - 16:00 Michael Sattler
Molecular recognition and dynamics in splicing regulation
16:00 - 16:45  Janusz Bujnicki
Structural bioinformatics of the spliceosome
16:50 – 17:00   Coffee break
17:00 – 19:00   Poster Session
19:00 Dinner

Saturday, Feb. 16

08:30 - 09:30     Registration
Session VIII (Chairperson: Holger Stark)
09:00 - 09:45        Oscar Llorca
Transient geometries in nonsense-mediated mRNA decay (NMD) visualized by cryo-EM
09:45 - 10:30   Elisa Izaurralde
mRNA quality control:  protecting cells from aberrant mRNA function
10:30 – 11:00 Coffee Break 
Session IX (Chairperson: Ralf Ficner)
11:00 - 11:10  Florian Heyd
Rhythmic U2AF26 alternative splicing regulates the circadian clock in mice
11:20 - 12:05  Ed Hurt
Structural and functional analyses of ribosome assembly
12:10 – 13:10 Lunch
13:10 End of the Symposium